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Hormonal disorders that cause high blood pressure include Cushing syndrome a disorder characterized by high levels of cortisol , hyperthyroidism an overactive thyroid gland , hyperaldosteronism overproduction of aldosterone, often by a tumor in one of the adrenal glands , and, rarely, a pheochromocytoma a tumor that is located in an adrenal gland and that produces the hormones epinephrine and norepinephrine.